d-Amino acids and kidney diseases
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چکیده
منابع مشابه
Biological role of D-amino acid oxidase and D-aspartate oxidase. Effects of D-amino acids.
D-Amino acids administered to animals are absorbed by the intestine and transported through the blood-stream to solid tissues where they are oxidized in vivo by D-amino acid oxidase and D-aspartate oxidase to produce the same compounds they do in vitro; i.e. NH3, H2O2, and the keto acid corresponding to the amino acid ingested. In the liver and kidneys of the animals, an inverse relationship ex...
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Bacteria form communities known as biofilms, which disassemble over time. In our studies outlined here, we found that, before biofilm disassembly, Bacillus subtilis produced a factor that prevented biofilm formation and could break down existing biofilms. The factor was shown to be a mixture of D-leucine, D-methionine, D-tyrosine, and D-tryptophan that could act at nanomolar concentrations. D-a...
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We isolated a thermophile, Bacillus sp. YM-1 which abundantly produced the thermostable D-amino acid aminotransferase (EC 2.6.1.21; D-AAT), and cloned the enzyme gene into E. coli. The primary structure of D-AAT was found to be homologous with that of branched-chain L-amino acid aminotransferase (EC 2.6.1.42; BCAT) of E. coli. Both enzymes are unique in their stereospecificity of proR C-4' hydr...
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D-amino acids have been detected in a variety of peptides synthesized by animal cells. These include opiate and antimicrobial peptides from amphibian skin, neuropeptides from snail ganglia, a hormone from crustaceans, and a constituent of a spider venom. cDNA cloning has shown that at those positions where a D-amino acid is found in the end-product, a normal codon for the corresponding L-amino ...
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Background: Diabetes mellitus is one of the most common endocrine diseases. Cardiovascular disease (CVD) is one of the leading causes of death in patients with type 2 diabetes. The aim of this study was to investigate the metabolic profile of plasma amino acids in diabetic patients with cardiovascular disease. Methods: The present study is a descriptive-analytical cross-sectional study on 140 ...
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ژورنال
عنوان ژورنال: Clinical and Experimental Nephrology
سال: 2020
ISSN: 1342-1751,1437-7799
DOI: 10.1007/s10157-020-01862-3